Retrospective Chart Reviews in Clinical Research: Methods, Challenges, and Best Practices
A Retrospective Chart Review (RCR) is a research approach that involves collecting and analyzing data from existing medical records to investigate clinical outcomes, treatment effectiveness, adverse events, or healthcare utilization patterns. Unlike prospective studies, RCRs analyze pre-recorded data, enabling faster study completion at a lower cost but requiring careful attention to bias, data quality, and ethical standards.
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