Use of Electronic Health Records (EHRs)

Using Electronic Health Records (EHRs) in Clinical Research: Opportunities, Challenges, and Best Practices

May 4, 2025

Electronic Health Records (EHRs) are digital systems for recording patient health information, including medical history, diagnoses, medications, lab results, and treatment plans. EHRs offer a rich source of real-world data (RWD) that can be repurposed for clinical research to generate real-world evidence (RWE). EHR-based studies can inform regulatory approvals, post-marketing surveillance, comparative effectiveness research, and healthcare quality improvement initiatives.
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Real-World Evidence (RWE) and Observational Studies, Use of Electronic Health Records (EHRs)

Using EHRs to Generate Real-World Evidence in Pharma Research

July 22, 2025

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Unlike controlled clinical trials, EHRs capture patient data in real-world clinical settings. This includes information on patient demographics, diagnoses, procedures, lab results, medications, comorbidities, and healthcare utilization.
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Real-World Evidence (RWE) and Observational Studies, Use of Electronic Health Records (EHRs)

Data Linkage Between EHRs and Claims Data for Real-World Evidence

July 22, 2025

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Each data source offers complementary strengths:
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Real-World Evidence (RWE) and Observational Studies, Use of Electronic Health Records (EHRs)

Standardization of EHR Data for Research Purposes in Pharma

July 23, 2025

digi

Raw EHR data comes from diverse sources—hospital systems, outpatient clinics, specialty centers, and labs. Each source may use different formats, terminologies, and data entry practices. Standardization ensures:
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Real-World Evidence (RWE) and Observational Studies, Use of Electronic Health Records (EHRs)

Ensuring Patient Privacy and De-Identification in EHR-Based Research

July 23, 2025

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Failure to properly secure or anonymize EHR data can lead to:
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Real-World Evidence (RWE) and Observational Studies, Use of Electronic Health Records (EHRs)

Regulatory Acceptance of EHR-Derived Data in Pharma Studies

July 23, 2025

digi

Agencies such as the FDA and EMA are open to the use of EHR data, provided the following criteria are met:
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Real-World Evidence (RWE) and Observational Studies, Use of Electronic Health Records (EHRs)

AI and NLP Applications in EHR Data Mining for Real-World Evidence

July 24, 2025

digi

EHR systems contain:
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Real-World Evidence (RWE) and Observational Studies, Use of Electronic Health Records (EHRs)

Common Data Models for EHR Integration in Real-World Evidence Studies

July 24, 2025

digi

Inconsistent EHR formats across healthcare systems hinder large-scale observational studies. CDMs solve this problem by:
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Real-World Evidence (RWE) and Observational Studies, Use of Electronic Health Records (EHRs)