Cluster Randomized Trials: Design, Methodology, and Best Practices in Clinical Research
Cluster Randomized Trials: Design, Methodology, and Best Practices in Clinical Research Comprehensive Overview of Cluster Randomized Trials in Clinical Research Cluster randomized trials (CRTs) offer a strategic design for evaluating interventions applied at a group level rather than to individual participants. By randomizing entire groups—such as hospitals, schools, or communities—rather than individuals, CRTs are particularly…