Tag: EHR mining

Leveraging Big Data Analytics for Orphan Drug Development

August 22, 2025

Leveraging Big Data Analytics for Orphan Drug Development Accelerating Orphan Drug Development Through Big Data Analytics The Role of Big Data in Rare Disease Research Rare diseases affect fewer than 200,000 individuals in the United States, yet over 7,000 rare diseases collectively impact more than 350 million people worldwide. Orphan drug development is complicated by…

Data & Technology, Rare and Orphan Disease Trials

Mining Electronic Health Records for Rare Disease Patient Identification

August 21, 2025

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Mining Electronic Health Records for Rare Disease Patient Identification Unlocking the Potential of Electronic Health Records for Rare Disease Trials Why Electronic Health Records Matter in Rare Disease Research Identifying eligible patients for rare disease clinical trials is one of the greatest barriers in orphan drug development. Unlike common diseases with large patient databases, rare…

Data & Technology, Rare and Orphan Disease Trials

Using AI to Identify Rare Disease Trial Candidates

August 20, 2025

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Using AI to Identify Rare Disease Trial Candidates Harnessing Artificial Intelligence to Improve Rare Disease Trial Candidate Identification The Challenge of Identifying Patients in Rare Disease Trials Recruiting patients for rare disease clinical trials is notoriously difficult due to low prevalence, heterogeneous clinical presentations, and long diagnostic odysseys. Traditional recruitment methods often fail because they…

Data & Technology, Rare and Orphan Disease Trials

Using Real-World Data to Inform Disease Progression in Rare Conditions

August 13, 2025

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Using Real-World Data to Inform Disease Progression in Rare Conditions Leveraging Real-World Data to Understand and Model Disease Progression in Rare Diseases Introduction: The Value of Real-World Data in Rare Disease Trials Understanding disease progression is one of the foundational steps in rare disease clinical research. However, the scarcity of patients, heterogeneity in symptoms, and…

Natural History Studies, Rare and Orphan Disease Trials