Bias and Interpretation Issues in Single-Arm Trials – Clinical Trial Design and Protocol Development
Bias and Interpretation Issues in Single-Arm Trials – Clinical Trial Design and Protocol Development “Challenges of Bias and Interpretation in Single-Arm Trials” Introduction Single-arm trials have become increasingly popular in clinical research, primarily when evaluating the efficacy of new treatments in rare diseases or severe conditions where a placebo control could be deemed unethical. In…