Imputation Methods in Clinical Trials: LOCF, MMRM, and Multiple Imputation
Imputation Methods in Clinical Trials: LOCF, MMRM, and Multiple Imputation How to Use LOCF, MMRM, and Multiple Imputation in Clinical Trials Handling missing data in clinical trials is a critical challenge that can significantly affect the integrity and reliability of study results. Patient dropouts, missed visits, and unrecorded outcomes are common, and how we address…
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