Single-Arm Trials: Design, Applications, and Best Practices in Clinical Research
Single-Arm Trials: Design, Applications, and Best Practices in Clinical Research Comprehensive Overview of Single-Arm Trials in Clinical Research Single-arm trials (SATs) offer a pragmatic design for evaluating the efficacy and safety of interventions when randomized controls are impractical, unethical, or infeasible. Especially prominent in oncology, rare diseases, and early-phase drug development, single-arm designs enable rapid…
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