P-value Thresholds in Interim Decisions
P-value Thresholds in Interim Decisions Understanding P-value Thresholds in Interim Decisions for Clinical Trials Introduction: Why P-value Thresholds Matter Interim analyses allow sponsors and Data Monitoring Committees (DMCs) to make informed decisions about whether to continue, modify, or terminate a clinical trial. At the heart of these analyses lies the p-value threshold—the cut-off that determines…