Confidence Interval Overlap Scenarios in Interim Analyses
Confidence Interval Overlap Scenarios in Interim Analyses Confidence Interval Overlap Scenarios in Interim Stopping Decisions Introduction: Confidence Intervals as Decision Tools While p-values are widely used in interim analyses, regulators and statisticians increasingly rely on confidence intervals (CIs) to interpret treatment effects and guide stopping decisions. Unlike single point estimates, CIs provide a range of…
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