Umbrella Trials Targeting Multiple Biomarker-Defined Subtypes
Umbrella Trials Targeting Multiple Biomarker-Defined Subtypes Designing Umbrella Trials for Multiple Biomarker-Defined Cancer Subtypes Introduction to Umbrella Trials Umbrella trials are an innovative clinical trial design in which multiple targeted therapies are evaluated simultaneously in a single disease setting, each therapy matched to a biomarker-defined patient subgroup. Unlike basket trials, which are tumor-agnostic, umbrella trials…
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